메뉴 바로가기 본문 바로가기

TEST ITEMS

THE GENERATION DIAGNOSTIC SYSTEM

Tn-I

Cardiac troponins are currently the most sensitive and specific biochemical markers of myocardial necrosis. There are three types of troponin in heart muscle fibers. Those are troponin-C, -I, and -T. Together they contribute to make cardiac muscle fibers contract. The clinical measurement of serum Tn-I has become an important tool in the diagnosis of acute myocardial infarction. Serum Tn-I is a more reliable than creatine kinase as a prognostic marker in people with ischemic chest pain. National and international scientific organizations have suggested the use of troponins, Tn-I and Tn-T, when implementing new diagnostic strategies in patients with acute coronary syndrome.

References

  • 1. Mauro Panteghini, Franca Pacani, Kiang-Teck J.Yeo, Fred S. Apple, Robert H. Christenson. Francesco Dati, Johannes Mair, Jan Ravkilde, and Alan H.B. We. Evaluation of Imprecision for Cardiac Troponin Assays at Low-Range Concentrations. 2004;50:2:327-332.
  • 2. Alan McNeil, PhD, FRACP, FRCPA. The Trouble with Troponin. Heart, Lung and Circulation 2007;16;S13-S16.
  • 3. David M. Bunk and Micahel J. Welch. Characterization of a New Certified References Material for Human Cardiac Troponin I. Clinical Chemistry 2002;52:2:212-219
  • 4. Jaffe AS, Ravkilde J, Roberts R, Naslund U, Apple FS, Galvani M, Katus H. It’s time for a change to a troponin standard. Circulation 2000;102:1216 –1220.
  • 5. Jillan R. Tate, David Heathcote, Gus Koerbin, Gary Thean, David Andriske, Jone Bonar, Janice Gill. Theharmonization of cardiac troponin I measurement is independent of sample time collection but is dependent on the source of calibrator. Clinica Chimica Acta 324:2002:13-23.
  • 6. Ohman EM, Armstrong PW, Christenson RH, et al. Cardiac troponin T levels for risk stratification in acute myocardial ischemia. N Engl J Med 1996;335:1333– 41.
  • 7. Antman EM, Tanasijevic MJ, Thompson B, et al. Cardiacspecific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes. N Engl J Med 1996;335:1342 –9.

ichroma™

Compatible Device ichroma™ I/II
Detection Range 0.1~50ng/mL
Sample Type Serum, Plasma
CV <10%
Comparability 0.989
Reaction Time 12Min

AFIAS

Compatible Device AFIAS-1/6
Detection Range 0.1~50ng/mL
Sample Type Whole Blood,
Serum, Plasma
CV <10%
Comparability 0.992
Reaction Time 12Min

Product News