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TEST ITEMS

THE GENERATION DIAGNOSTIC SYSTEM

HBsAg

The hepatitis B virus (HBV) is responsible for hepatic lesions, as in fulminant acute hepatitis or chronic hepatitis that can result in cirrhosis and hepatocellular carcinoma. Detection of the Hepatitis B virus surface antigen (HBsAg) in serum or plasma indicates an infection caused by the hepatitis B virus. It is the first marker to appear during the course of the disease[1]. Clinical and biological symptoms appear two to three weeks after the initial infection with HBV. Presence of HBsAg can be as short as a few days or as long as several years. If HBsAg persists for more than six months, the hepatitis is classified as ‘chronic’. Due to existence of numerous asymptomatic chronic carriers, screening for HBsAg is required for each blood donation and for each pregnancy to enable the newborns of the carrier mother to receive prophylactic treatment.[2,3]

References

  • 1. Performance evaluation of immunoassay detection of HBsAg mutants and their clinical significance in the high risk groups. Jung-in Choi et al., Lab Med Online., 2013, 3:88-96
  • 2. Centers for Disease Control and Prevention. Recommendations of the Immunization Practices Advisory Committee Prevention of Perinatal Transmission of Hepatitis B Virus: Prenatal Screening of all Pregnant Women for Hepatitis B Surface Antigen. MMWR, 1988; 37: 341-355.
  • 3. Centers for Disease Control and Prevention. Hepatitis B Virus: A comprehensive Strategy for Eliminating Transmission in the United States Through Universal Childhood Vaccination: Recommendations of the Immunization Practices Advisory Committee (ACIP), MMWR, 1991; 40:1-19.

ichroma™

Compatible Device ichroma™ II
Detection Range COI ≥ 1.0
Sample Type Whole Blood,
Serum, Plasma
CV
Comparability 1.0
Reaction Time 12Min

AFIAS

Compatible Device AFIAS-1/6
Detection Range COI ≥ 1.0
Sample Type Whole Blood,
Serum, Plasma
CV
Comparability 0.996
Reaction Time 12Min

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