Colorectal cancer is the third most common cancer in the world, with about 1 million new cases and more than 500, 000 deaths per year. Screening method for colorectal cancer include the immuno chromatography fecal occult blood (iFOB) test, barium enema, sigmoidoscopy and colonoscopy. Large randomized controlled trials have shown that iFOB screening can result in decreased colorectal cancer mortality[3,4]. The traditional FOB test uses the chemical Guaiac, which is sensitive to Hb peroxidase activity. However, the Guaiac-FOB test has low sensitivity to clinically significant colorectal neoplasis and has low specificity due to its non-specificity for human Hb[5,6]. To overcome these potential problems in immunochemical test, ichroma™ iFOB Neo uses specific monoclonal antibodies against human Hb. The patient is not forced to avoid food or medicine before the iFOB is tested. ichroma™ iFOB Neo contains a stabilized extraction buffer tube which can be stored in room temperature.