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TEST ITEMS

THE GENERATION DIAGNOSTIC SYSTEM

Cystatin-C

The level of serum cystatin C has been proposed as a simple, accurate, and rapid endogenous marker of glomerular filtration rate (GFR) in research and clinical practice. The measurement of serum cystatin C may detect mild to moderate decrease in GFR that are not evident with the serum creatinine measurement. In kidney transplant patients, cystatin C was reported to be more sensitive than serum creatinine for detecting decreases in GFR and delayed graft function, offering an opportunity for timely intervention.

References

  • 1. Laterza OF, Price CP, Scott MG. Cystatin C: an improved estimator of glomerular filtration rate? Clin Chem 2002; 48: 699- 707.
  • 2. Shemesh O, Golbetz H, Kriss JP, Myers BD. Limitations of Creatinine as a filtration marker in glomerulopathic patients. Kidney Int 1985;28: 830-8.
  • 3. Abrahamson M, Olafsson I, Palsdottir A, Ulvsback M, Lundwall A, Jensson O, et al. Structure and expression of the human cystatin C gene. Biochem J 1990; 268: 287-94.
  • 4. Newman DJ: Cystatin C. Ann Clin Biochem 2002; 39: 89-104.
  • 5. Kazama JJ, Kutsuwada K, Ataka K, Maruyama H, Gejyo F. Serumcystatin C reliably detects renal dysfunction in patients

ichroma™

Compatible Device ichroma™ I/II
Detection Range 0.1~7.5 mg/L
Sample Type Whole Blood,
Serum, Plasma
CV <10%
Comparability 0.98
Reaction Time 10Min

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